Protect Research Integrity: How to Spot Issues Early and Build a Proactive Integrity Culture

Research integrity is under increasing pressure. Submission volumes are rising, manipulation techniques are becoming more sophisticated, and editorial teams are expected to make decisions faster than ever.

In our recent webinar, “Protect Research Integrity: How to Spot Issues Early and Build a Proactive Integrity Culture,” Abdallah Asad, Co-Founder and COO of MindCrafted Analytics, and Patrick Starke, Co-Founder and CEO of Imagetwin, discussed how publishers, editors, and research institutions can move from reactive investigations to proactive integrity screening. In case you missed the live session, we would like to share the main insights.

The Growing Pressure on Editorial Teams

Today, journals receive more submissions each year, while the number of qualified reviewers and editorial experts remains limited. As Patrick Starke explained during the webinar, this creates a major bottleneck:

“Manual checks are becoming a limiting factor. Even well-established publishers struggle because there simply aren’t enough trained experts to review everything.”

Editors today must assess manuscripts across multiple dimensions:

  • image integrity
  • plagiarism
  • statistical validity
  • citation manipulation
  • data authenticityEach area requires different expertise. 

 

Each area requires different expertise. This is why many publishers are now turning to automated research integrity tools that can support editors by identifying potential issues earlier in the editorial process.

Structural Gaps in Research Integrity Workflows

According to Abdallah Asad, the integrity challenge is a structural weakness in editorial workflows. He highlighted three key gaps commonly seen across journals and institutions.

1. Policy gaps

Many journals reference COPE (Committee on Publication Ethics) guidelines. However, these policies often remain static documents rather than operational processes. Without clear implementation, policies alone cannot prevent integrity issues.

2. Reactive handling of misconduct

In many cases, journals only investigate integrity problems after complaints are raised or misconduct is reported publicly. By that point, reputational damage may already have occurred.

3. Inconsistent editorial workflows

Publishing is one of the oldest industries in the world. While submission systems have moved online, many editorial workflows have not evolved at the same pace.

This can lead to:

  • unclear responsibilities
  • missing integrity checkpoints
  • inconsistent review processes across journals

Why Integrity Checks Should Happen Earlier

Historically, many journals screened manuscripts for integrity issues late in the editorial process, sometimes only at the acceptance stage. In some cases, integrity checks were skipped entirely. Today, to address this, many publishers are moving integrity screening to the submission stage. Early screening has several advantages:

  • problematic manuscripts can be flagged before peer review
  • reviewers spend time only on reliable submissions
  • editors can address issues before publication

The Role of Automated Image Integrity Screening

One area where automation is already making a significant impact is image integrity analysis. Scientific images such as western blots, microscopy images, and gel electrophoresis figures are particularly vulnerable to duplication, manipulation, inappropriate editing, and AI generation. Imagetwin uses AI-based analysis to detect these issues automatically.

Partnerships Are Key for Scalable Integrity

Another important theme discussed during the webinar was the role of partnerships in scaling research integrity practices.

MindCrafted Analytics provides the Rivyr publishing infrastructure, which supports the full editorial workflow from submission to production. By integrating Imagetwin’s screening capabilities into Rivyr, publishers can embed automated image checks directly into their editorial processes. This type of integration offers several benefits:

  • automated integrity checks within submission systems
  • reduced manual workload for editors
  • consistent screening across journals

Handling Detected Integrity Issues

Another important question raised during the webinar was what should happen after integrity issues are detected. If image duplication or manipulation appears to be a simple mistake, authors may be asked to provide corrections. However, if manipulation appears intentional, editors may need to investigate more deeply. As Patrick explained, correcting a single problematic image does not necessarily resolve the issue: “If some parts of the data are manipulated, can we still trust the rest of the study?”

This highlights why clear editorial policies and investigation procedures are essential. COPE guidelines provide frameworks for handling:

  • corrections
  • expressions of concern
  • retractions

Sustainability of AI-Based Integrity Screening

One interesting question from the audience focused on the environmental cost of AI infrastructure. Image integrity detection can require significant computational resources, particularly when comparing images across millions of research figures. Imagetwin addresses this by running its infrastructure on cloud servers powered by renewable energy, while continuously optimizing models to reduce compute requirements.

Moving Toward Proactive Research Integrity

A central takeaway from the webinar was clear: Research integrity cannot rely solely on trust or manual oversight. Instead, publishers and institutions need:

  • structured editorial workflows
  • defined responsibilities
  • standardized integrity checkpoints
  • automated screening tools

When these elements are combined, journals can move from reactive investigations to proactive prevention. If you missed the live discussion, you can watch the full webinar recording here.